But although the article does not really fulfill its stated purpose, it provides excellent information on the working of the disease and possible treatments ad cures. A few of the symptoms caused by sickle-cell anemia include stroke, infections, bone damage, lung blockage, eye damage, and delayed growth. Similar observations were made on echocardiography, with subjects over the age of 23 demonstrating an abnormal ejection fraction compared to the younger group, despite enhanced end-diastolic diameter. It is composed of 4 protein subunits, two called Alpha — globin and two called Beta-globin. The sickle cell disorder is a longtime disease that may result in some health problems because of low oxygen that the blood is flowing in the circulatory system. The inset image shows a cross-section of a sickle cell with long polymerized HbS strands stretching and distorting the cell shape. This is very dangerous as it may cause damage to the retina, which is responsible for processing visual images.
Infected red blood cells are not able to supply enough of nutrients and oxygen to the body and this slows growth in children and teenagers may even have delayed puberty. Great real estate agent business plan templates + layout of research paper with an abstract problem solving framework kaplinsky critical thinking book 1 pdf business continuity planning pdfWatson glaser critical thinking test answers test should students have homework pros jane eyre essay coming of age free dissertation download full. If you have sickle cell disease you have an abnormal type of hemoglobin. How many people have sickle cell disease, what challenges they face personally and socially? The sickle cells also block the flow of blood through vessels resulting in lung tissue damage acute chest syndrome , pain episodes arms, legs, chest and abdomen , stroke and priapism painful prolonged erection. As a result of this erratic unbalanced physical condition, the patient came into the hospital emergency last month complaining of abdominal pain along with spiking body temperatures ranging between 99.
In order for sickle cell anemia to occur, a sickle cell gene must be inherited from both the mother and the father, so that the child has two sickle cell genes Shiel, 2006, para. Obviously, not every company on the web is safe, and even fewer have both low prices and high-quality papers. There are many diseases of the blood that have been passed down from older generations. This is what causes the complications of sickle cell disease. The abnormal hemoglobin causes distorted sickled red blood cells. The affected red blood cells also stick to the blood vessels and may lead to clogging to these vessels. Yes, the strongest pain medicine in hospital is needed to lessen the pain.
Sickle Cell Anemia Research Papers Sickle Cell Anemia Research Papers look at one of the most common inherited blood disorders. Sickle cell disease is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. The Sickle cells causes a blockage which stops the flow of blood. Sickle red blood cells become hard, sticky and shaped like sickles used to cut wheat. The red cell sickle is made from a substance in the red cell called hemoglobin that carries oxygen into the cell. Hemoglobin is found on red blood cells and it is used to provide oxygen to tissues Peachley, n.
Gene therapy fulfilling its promise. This is what causes Hemolytic Anemia. Sickle cell is a lifelong battle that causes pain, infection, anemia, and even a stroke. This is probably due to the continued decline in HbF level in adults and the heterocellular and variable distribution of HbF amongst F-cells. Sickle-cell disease Classification and external resources Figure A shows normal red blood cells flowing freely through veins.
The HbB gene that codes for the beta chain or beta globin, is located at the 15. Blocked blood flow can cause pain, serious infections, and organ damage. It is basically the sickling of erythrocytes. Without a cure for the disease, there is much doctors can still do to help sickle-cell patients, and treatment is constantly being improved. Sickle cell anemia is an inherited disease in which the body is unable to produce normal hemoglobin, an iron-containing protein.
Sickle cell trait is not a type of sickle cell disease. This article bridges these theoretical-evolutionary and clinical-racial narratives by focusing on the discovery of sickle cells in marginalized Arabic-speaking communities of Yemen and Turkey in the 1950s. This causes red blood cells to become stiff and C-shaped. The most common and serious complications of sickle cell disease are anemia, pain, fatigue, and organ failure. Since harvesting embryonic stem cells necessitates destroying the embryo from which those cells are obtained, the moral status of the embryo comes into question. There are several types of sickle cell disease.
Oxygen is delivered throughout the body to all the vital organs. Knowing the basics of stem cells is a necessity to understanding how they might positively impact those with a medical condition. How to solve integration problems with limitsHow to solve integration problems with limits 30 60 90 day sales business plan web assign help desk susan sontag essays online planning for a dissertation themed writing paper second grade dissertation topics in financial management training. Laboratory and empirical findings have proffered some solutions and treatments yet the result still seems to be far from conclusion. The cells become clogged, due to their crescent shape, which keeps them from delivering oxygen.
The red blood cells, which are normally shaped like a discs, takes on a sickle or crescent shape, therefore called sickle-shaped. The results apply to both areas, of course, but the article could detail the effects of treatment more. The stickiness is then exposed to the epithelial cells of blood vessels, and can stick to them, forming clumps and eventually clots which, in the right or wrong place, could lead to a stroke. This is the reason the person feels fatigued, has shortness of breath, and looks pale. The mutation that causes sickle cell anemia is often referred to as the sickle cell trait. Monitoring of the progress of the disease is the best way to prevent stroke that the author provides, other than regular transfusions in children with a certain type of the disease.
In the deoxygenated form, it forms into long arrays that come out the shape of the red cell and produce the characteristic sickling that characterizes the disease. If you would like this paper removed from our website, please contact us our Contact Us Page. This article outlines recent evidence that suggests simply preventing the hemoglobin from twisting could also prevent it from forming into needles, ending the problem. To understand about embryonic stem cell. Sickle cell comes from a farm tool with a curved blade.